• Users Online: 83
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2016  |  Volume : 33  |  Issue : 1  |  Page : 19-23

Undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma of the larynx with giant cells and myogenic differentiation: a case report


1 Histopathology Department, King Khalid Hospital, Hail, Kingdom of Saudi Arabia
2 Surgery Department, King Khalid Hospital, Hail, Kingdom of Saudi Arabia

Correspondence Address:
Laila Seada
Professor, Histopathology Department, Faculty of Medicine, Benha University, Qalyoubia Province, 13518
Kingdom of Saudi Arabia
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1110-208X.194383

Rights and Permissions

Undifferentiated pleomorphic sarcoma (UPS)/malignant fibrous histiocytoma (MFH) is quite rare in the larynx, with few cases reported. In the present study, we report an UPS/MFH of the larynx arising as a second primary neoplasm. It showed giant cells, spindle areas with vague storiform appearance, and myxoid areas. CD68 was positive in the giant cells and focally in the tumor cells. S100 showed scattered positivity in stellate cells. Desmin and specific muscle actin were negative, whereas h-caldesmon was positive in tumor cells and medium-sized blood vessels, denoting a possible myogenic differentiation. To the best of our knowledge this is one of the rare case reports of UPS/MFH with giant cells in the larynx arising as a second primary neoplasm.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed369    
    Printed0    
    Emailed0    
    PDF Downloaded56    
    Comments [Add]    

Recommend this journal