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ORIGINAL ARTICLE
Year : 2018  |  Volume : 35  |  Issue : 2  |  Page : 214-217

Corneal epithelial thickness changes as imaged by Fourier-domain optical coherence tomography in eyes with keratoconus


Ophthalmology Department, Faculty of Medicine, Benha University, Benha, Egypt

Correspondence Address:
Dr. Ahmed Y Fekry
Flat 8, Floor 3, 24 El Gomhoria St, El Mansourah, 35511
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/bmfj.bmfj_46_17

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Purpose The purpose of this study was to document changes in the corneal epithelium as imaged by Fourier-domain optical coherence tomography (OCT) in cases of keratoconus. Patients and methods This is a comparative cross-sectional study including 20 eyes of 14 patients with keratoconus (n=20, study group) and 16 eyes of eight normal individuals (n=16, control group). Both groups were imaged using Scheimpflug imaging corneal topography and Fourier-domain AS-OCT system. Corneal epithelial thickness maps obtained by the AS-OCT system were studied and compared between the two groups. Results There was no statistically significant difference in mean corneal epithelial thickness between study and control groups (unpaired Student’s t-test, P<0.05). Minimum corneal epithelial thickness was statistically significantly less and maximum corneal epithelial thickness was statistically significantly more in the study group compared with the control group (unpaired Student’s t-test, P<0.05). Corneal epithelial thickness was least in the central, temporal, and inferotemporal sectors of the study group. A distinct pattern of epithelial thinning over the thinnest pachymetry and highest back elevation with varying degrees of surrounding epithelial thickening located in the inferotemporal quadrant was observed in 71.43% of the study group. Conclusion Recognizable corneal epithelial thickness changes are seen in keratoconic eyes. The diagnostic potential of such changes need to be further investigated.


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