• Users Online: 500
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2018  |  Volume : 35  |  Issue : 3  |  Page : 350-355

Thyroid dysfunction in patients with metabolic syndrome in medical ICU of Zagazig university hospitals


1 Internal Medicine Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt
2 Medical Biochemistry Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt

Correspondence Address:
Dr. Ayman M.E.M Sadek
Shoubak Basta, Zagazig, Sharkia province, 44519
Egypt
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/bmfj.bmfj_31_18

Rights and Permissions

Context Thyroid hormones are responsible for different metabolic processes. Hormonal imbalance is a suggested risk factor for metabolic syndrome (MS) development. Aim We aimed to explore the frequency of undiagnosed thyroid dysfunction (TD) among patients with MS in medical ICU and its relation to each component of MS, morbidity, and mortality. Settings and design We carried out a cross-sectional cohort study on patients who were admitted to medical ICU of Zagazig University Hospitals. Patients and methods Of 941 medical ICU patients admitted over 6 months, 106 patients had MS. We measured thyroid stimulating hormone (TSH), free T3, and free T4 for those patients within 48 h of admission and acute physiology and chronic health evaluation II score calculation within 24 h of admission, and then we followed them up for short-term in-hospital mortality. Results The frequency of TD in patients with MS was seen in 32 of 106 patients (90.6% of them were hypothyroid). We found an increased relative risk (RR) of 1.92-fold owing to the female sex. Logistic regression analysis revealed that obesity, hypertension, and hypercholesterolemia were the factors most associated with TD (P<0.001), with an increased RR by 1.25-, 1.45-, and 1.37-fold, respectively. Acute physiology and chronic health evaluation II score and mortality RR increased by 1.05 and 1.26-fold, respectively. Conclusion MS in women may carry a high risk for TD, especially hypothyroidism, with poor medical ICU prognosis.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed556    
    Printed93    
    Emailed0    
    PDF Downloaded84    
    Comments [Add]    

Recommend this journal